GHK-Cu
50 mg
Copper-binding tripeptide investigated for skin remodeling and tissue repair pathways.
Overview
GHK-Cu (Glycyl-L-Histidyl-L-Lysine bound to copper(II)) is a naturally occurring tripeptide first isolated from human plasma. It has been extensively studied for its role in extracellular matrix remodeling, wound healing models, and gene-expression modulation.
Mechanism of Action
GHK-Cu acts as a copper-delivery carrier across cellular membranes, where copper participates as a cofactor for lysyl oxidase and superoxide dismutase. The peptide modulates the expression of genes associated with tissue remodeling, anti-inflammatory signaling, and antioxidant defense. Research indicates upregulation of collagen, elastin, and glycosaminoglycan biosynthesis in dermal fibroblast cultures.
Research Findings
GHK Peptide as a Natural Modulator of Gene Expression
BioMed Research International, 2015 (PMC4488751)
Demonstrates GHK-Cu modulation of 4,000+ human genes related to repair and regeneration.
Copper Peptide GHK-Cu in Skin Studies
J. Cosmet. Dermatol., 2018
Reviews dermal fibroblast response and matrix protein synthesis.
Potential Research Applications
- Dermal fibroblast research
- Wound healing models
- Antioxidant pathway studies
- Hair follicle research
Often researched with
BPC-157
10 mg
Pentadecapeptide derived from gastric protein studied for systemic repair pathways.
TB-500
10 mg
Synthetic fragment of Thymosin Beta-4 studied for actin regulation and tissue repair.
Thymosin Beta-4
10 mg
Full-length actin-sequestering peptide for repair research.
Klow Blend
TB-500 + BPC-157 + GHK-Cu + KPV
Quad blend adding KPV anti-inflammatory tripeptide.