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Research GradeWeight Management & Metabolic

Tirzepatide

10 mg

Dual GIP/GLP-1 receptor agonist for metabolic research.

Overview

Tirzepatide is a dual GIP and GLP-1 receptor agonist developed for the study of glucose-dependent insulin secretion and weight regulation pathways.

Mechanism of Action

Tirzepatide engages GIP and GLP-1 receptors on pancreatic β-cells, potentiating glucose-stimulated insulin release while modulating glucagon secretion. Central GLP-1R activation in hindbrain nuclei contributes to satiety signaling.

Research Findings

Tirzepatide Once Weekly for the Treatment of Obesity

NEJM, 2022 (PMID: 35658024)

SURMOUNT-1 trial outcomes.

Potential Research Applications

  • Incretin research
  • Glycemic regulation studies
  • Adiposity models