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Research GradeAppearance & Skin Health
Melanotan I
10 mg
α-MSH analogue studied for melanogenesis research.
Overview
Melanotan I (Afamelanotide) is a synthetic α-MSH analogue with enhanced melanocortin-1 receptor affinity.
Mechanism of Action
Agonizes MC1R on melanocytes, increasing cAMP and stimulating eumelanin biosynthesis through MITF and tyrosinase pathway upregulation.
Research Findings
Afamelanotide and Melanogenesis
NEJM, 2015
MC1R-mediated pigmentation pathways.
Potential Research Applications
- Melanocortin receptor research
- Photoprotection studies