Research GradeWeight Management & Metabolic

Ipamorelin

5 mg

Selective ghrelin receptor agonist studied for GH release.

Overview

Ipamorelin is a pentapeptide ghrelin/GHS-R1a agonist that selectively stimulates growth hormone secretion without significant effects on cortisol or prolactin.

Mechanism of Action

Binds GHS-R1a on pituitary somatotrophs, activating PLC/IP3 signaling and triggering GH release. Lack of cross-reactivity with cortisol-related receptors distinguishes its profile.

Research Findings

Selective GH Release by Ipamorelin

Eur. J. Endocrinol., 1998

Receptor selectivity profile.

Potential Research Applications

Selective GH research
Ghrelin receptor studies

Often researched with

CJC-1295

5 mg

GHRH analogue studied for growth-hormone axis research.

Growth Stack

CJC-1295 2 mg + Ipamorelin 2 mg

GHRH + GHRP combination for somatotropic research.

Tesamorelin

5 mg

Stabilized GHRH analogue for visceral adiposity research.