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Research GradeMetabolic & Cellular Health
IGF-1 LR3
1 mg
Long R3 IGF-1 analogue for growth pathway research.
Overview
IGF-1 LR3 is an 83-amino-acid analogue of insulin-like growth factor 1 with Arg→Glu substitution and N-terminal extension for extended half-life.
Mechanism of Action
Engages IGF-1R with reduced affinity for IGF-binding proteins, prolonging receptor activation and downstream PI3K/AKT/mTOR signaling.
Research Findings
IGF-1 LR3 Pharmacology
Growth Hormone IGF Res., 2002
Binding protein interaction profile.
Potential Research Applications
- IGF-1R signaling research
- Hypertrophy pathway studies